A Pilot Study Of Microsporidiosis And CD4 T-Ceils In North- Central, Nigeria

Two species of Microsporidia were Identified: (Enterocytozoon bieneusi and Encephalitozoon cunlpuli) among .the non-HIV. and. immunocompromised individuals at the Jos. Plateau, and Benue State, Nigeria. In Jos, 500 species were subjected to laboratory test and the Infection rate of microsporidium species were 1(0.5%) for gastroenterilis with <350 cell/pl;. 15(15.0%) .were HIV individuals with <200 cell/ |j|; and -19(19.0%) AIDS patients had low CD4 counts (<100 cell/, pi). The severity of the illness was seen to have impact on the GD4 counts of the individuals in Makurdi where,. in both sexes 5(3.5%) students had <100 cells/ pi CD4 counts with corresponding fail in 36(5.7%)-Civil servants of <100 ’cells/ pi cells count* Housewives were 44(6.8%) with <50 cells/ pi, and others (undefined occupational status) 11(1.5%) had CD4.counts'<90 cell/ pL Microsporidiosis is'now known to .' cause a serious threat in HIV/AIDS patients in Nigeria.with less pathogenesis among non-HIV individuals hence, P<±1:96. critical region, we.-accept that,, there was'a significant difference in the distribution of Microsporidiosis among sexes'In Makurdi with the x2=0.59<7.8-at '5% level of significance (indicating a significant difference in sex related prevalence at the Jos, Plateau), However, there was’high level of social, behavior-observed al'Makurdi with a general low CD4 counts (<50 cell/pl-<100 cell/pi).