Antimicrobial Resistance Profile and Quinolone Resistance Genes in Staphylococcus aureus from Patients Attending Federal Medical Centre Keffi, Nigeria

Aims: This study investigated the antimicrobial resistance profile and quinolone resistance genes in Staphylococcus aureus from patients attending Federal Medical Centre, Keffi, Nigeria. Methodology: A total of 240 clinical samples which comprised of high vaginal swabs, endocervical swabs, sputum, ear swabs, wound swabs, semen and eye swabs, were collected from the patients. Staphylococcus aureus was isolated and identified from these samples using standard microbiological method. Antimicrobial susceptibility testing of the isolates was performed and interpreted in accordance with the Clinical and Laboratory Standards Institute (CLSI) method. Ciprofloxacin-resistant S. aureus were screened for quinolone resistance genes using Polymerase Chain Reaction (PCR) method