SYNTHESIS AND FLUORESCENCE CHARACTERISTICS OF 2-A-ANILINOPURINE, 2-/VPIPERIDINOPURINE, 6-A-ANILINOPURINE AND 6-A-PIPERIDINOPURINE

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2008-08-01

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FACULTY OF NATURAL AND APPLIED SCIENCE NASARAWA STATE UNIVERSITY, KEFFI.

Abstract

2-Fluoropurine was prepared from 2aminopurine through a diazotization reaction, followed by treatment with Jluoroboric acid. 2-Aminopurine was obtained from a series of reactions, using 5-nitrouracil as the starting material. 2- N-Piperidino and 2- N-anilinopurines were obtained by treating 2-fluoropurine with piperidine and aniline respectively. 6-N-Piperidino and 6-N-anilinopurines were obtained by treating 6-chloropurine with piperidine and aniline. Fluorescence studies were carried out in various solvents and maximum fluorescence was observed in 75% ethanol. 2- Aminopurine showed the highest fluorescence intensity, followed by 2-N-anilino and 2-N-piperidinopurines. 6- Substituted purines showed stronger fluorescence intensities compared to 2-substitutedpurines

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Piperidinopurine, anilinopurine, synthesis, fluorescence

Citation

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https://keffi.nsuk.edu.ng/handle/20.500.14448/5539

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