Comparative Evaluation of Phyto Chemical Composition and In-Vitro Antioxidant Activity of N-Hexane Extract Of Two Types of Ipomoea Batatas and Standard Nutraceutical

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dc.contributor.authorCarole, Nweze Chibuzor
dc.contributor.authorHaruna, Sunday Gambo
dc.contributor.authorUkamaka, Ijeomah Ann
dc.contributor.authorBamidele, James
dc.contributor.authorIliasu, Muhammed Jimoh
dc.date.accessioned2023-12-14T06:38:20Z
dc.date.available2023-12-14T06:38:20Z
dc.date.issued2021-02-10
dc.description.abstractThe plant tuber, I. batatas may be regarded as a functional food if found to contain some beneficial bioactive compounds which may improve health and management of diseases. The current study comparatively evaluated the phytochemical composition, invitro antioxidant activity as well as free radical scavenging properties of n-hexane extract of white I. batatas and pink I. batatas with a standard synthetic nutraceutical. All analyses followed standard methods. Phytochemical analysis of the I. batatas revealed the presence of flavonoids, alkaloids, tannins, terpenoids, steroids, saponins and phenol in the extracts of the two I. batatas pecies. The 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity of the pink I. batatas (36.27±0.01, 38.71±0.01, 49.34±0.01, 53.59±0.01, 54.63±0.01) was significantly (p < 0.05) higher compared to the standard neutraceutical (39.18±0.01, 43.65±0.01, 43.93±0.01, 54.19±0.01, 57.24±0.01). Ascorbic acid (15.48±2.94 mg/dl) and Vitamin B2 (1.30±0.26 mg/dl) concentrations in the pink I. batata extract were significantly (p < 0.05) higher when compared to the standard Nutraceutical (11.81±8.04) and (1.16±0.02) resspectively. A higher percentage inhibition of the radical “ferric ion” by the white and pink I. batatas was higher when compared to the standard nutraceutical. The 2,2‟-Azinobis3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging activity was significantly (p < 0.05) higher by the white (75.19±0.01, 75.66±0.02, 73.56±0.01, 71.94±0.03, 69.36±0.01) and the pink (77.45±0.01, 75.22±0.01, 76.73±0.01, 74.64±0.01, 72.37±0.01) compared to the standard nutraceutical (74.17±0.01,74.36±0.01, 75.46±0.01, 74.28±0.01, 72.10±0.01). Hydrogen peroxide decomposition activity was also significantly (p < 0.05) higher in the white (55.59±0.02) and pink (57.63±0.01) I. batatas at 0.4 mg/ml sample concentrations compared to the standard nutraceutical. The results of this research showed that the white and pink I. batata extracts are rich in phytochemicals and vitamins and possess free radical scavenging and inhibiting abilities, indicating their prospects of being used as natural nutraceuticals and could serve as alternatives to the synthetic nutraceuticals which are often expensive and inaccessible by rural dwellers.en_US
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dc.identifier.urihttps://keffi.nsuk.edu.ng/handle/20.500.14448/5433
dc.language.isoenen_US
dc.publisherDepartment of Biochemistry, Nasarawa State University Keffien_US
dc.subjectPhytochemical, Nutraceutical, Ipomea batatas, Antioxidant, free radical, inhibition, scavenging, n-Hexane, In-Vitro.en_US
dc.titleComparative Evaluation of Phyto Chemical Composition and In-Vitro Antioxidant Activity of N-Hexane Extract Of Two Types of Ipomoea Batatas and Standard Nutraceuticalen_US
dc.typeArticleen_US

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