Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination tests

dc.contributor.authorAdoga, M.P.
dc.contributor.authorGyar, Dogara Silas
dc.contributor.authorPechulano, Simon
dc.contributor.authorBashayi, Obadiah D.
dc.contributor.authorEmiasegne, Samuel E.
dc.contributor.authorZungwe, Timothy
dc.contributor.authorIperepolu, Odunayo H.
dc.contributor.authorAgupugo, Chinwe
dc.contributor.authorAgwale, Simon M.
dc.date.accessioned2023-12-14T07:41:39Z
dc.date.available2023-12-14T07:41:39Z
dc.date.issued2010-04-23
dc.description.abstractBackground: In spile of the availability of an effective vaccine since I982 against hepatitis B. infection with hepatitis B virus (IIBV). which is 50 to 100 times more infectious than ] IIV. still persists in most parts of the world with Nigeria being described as an endemic /one. We therefore set out to establish the prevalence of this infection and evaluate its relationship with age and gender in urban Nigerians. Methodology: During pre-vaccination tests, blood samples were collected by linger-prick and venepuncture from 1.891 subjects aged < 60 years, between 2008 and 2009 after having obtained informed consent and ethical clearance. Smart Check MBsAg (Globalcmcd. Cape Town. South Africa) and ShantcstTM-HBsAg Elisa (Shanlha Biolcchnics Ltd, Hyderabad, India) were used for initial and confirmatory tests respectively. Results: Of the 1.891 participants. 957 (50.6 %) were males and 934 (49.4%) were females. Overall 114 (6.0%) were positive, of whom 71 (7.4%) were males and 43 (4.6%) females. Those aged 21-30 years had the highest infection rate, and males were more likely to be infected with the vims than females (P > 0 05). Conclusions: Such a high prevalence of a vaccine-preventable infection questions the effectiveness of the Nigerian vaccination strategies. The Nigerian government hepatitis B vaccination programme, which hitherto is limited to the National Childhood Immunisation Programme, should include the adult population.en_US
dc.identifier.citationGyar, D.S et al. (2010) Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination testsen_US
dc.identifier.urihttps://keffi.nsuk.edu.ng/handle/20.500.14448/5857
dc.language.isoenen_US
dc.publisherDepartment of Microbiology, Nasarawa State Uiniversity, Keffi.en_US
dc.subjectHepatitis B Vims: prevalence; vaccination; Nigeriaen_US
dc.titleHepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination testsen_US
dc.typeArticleen_US

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