Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination tests
| dc.contributor.author | Adoga, M.P. | |
| dc.contributor.author | Gyar, Dogara Silas | |
| dc.contributor.author | Pechulano, Simon | |
| dc.contributor.author | Bashayi, Obadiah D. | |
| dc.contributor.author | Emiasegne, Samuel E. | |
| dc.contributor.author | Zungwe, Timothy | |
| dc.contributor.author | Iperepolu, Odunayo H. | |
| dc.contributor.author | Agupugo, Chinwe | |
| dc.contributor.author | Agwale, Simon M. | |
| dc.date.accessioned | 2023-12-14T07:41:39Z | |
| dc.date.available | 2023-12-14T07:41:39Z | |
| dc.date.issued | 2010-04-23 | |
| dc.description.abstract | Background: In spile of the availability of an effective vaccine since I982 against hepatitis B. infection with hepatitis B virus (IIBV). which is 50 to 100 times more infectious than ] IIV. still persists in most parts of the world with Nigeria being described as an endemic /one. We therefore set out to establish the prevalence of this infection and evaluate its relationship with age and gender in urban Nigerians. Methodology: During pre-vaccination tests, blood samples were collected by linger-prick and venepuncture from 1.891 subjects aged < 60 years, between 2008 and 2009 after having obtained informed consent and ethical clearance. Smart Check MBsAg (Globalcmcd. Cape Town. South Africa) and ShantcstTM-HBsAg Elisa (Shanlha Biolcchnics Ltd, Hyderabad, India) were used for initial and confirmatory tests respectively. Results: Of the 1.891 participants. 957 (50.6 %) were males and 934 (49.4%) were females. Overall 114 (6.0%) were positive, of whom 71 (7.4%) were males and 43 (4.6%) females. Those aged 21-30 years had the highest infection rate, and males were more likely to be infected with the vims than females (P > 0 05). Conclusions: Such a high prevalence of a vaccine-preventable infection questions the effectiveness of the Nigerian vaccination strategies. The Nigerian government hepatitis B vaccination programme, which hitherto is limited to the National Childhood Immunisation Programme, should include the adult population. | en_US |
| dc.identifier.citation | Gyar, D.S et al. (2010) Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination tests | en_US |
| dc.identifier.uri | https://keffi.nsuk.edu.ng/handle/20.500.14448/5857 | |
| dc.language.iso | en | en_US |
| dc.publisher | Department of Microbiology, Nasarawa State Uiniversity, Keffi. | en_US |
| dc.subject | Hepatitis B Vims: prevalence; vaccination; Nigeria | en_US |
| dc.title | Hepatitis B virus infections in apparently healthy urban Nigerians: data from pre-vaccination tests | en_US |
| dc.type | Article | en_US |