Faculty of Natural And Applied Sciences

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Browsing Faculty of Natural And Applied Sciences by Author "Abah, E.J."

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    ANTIBIOTIC SUSCEPTIBILITY OF STAPHYLOCOCCUS AUREUS FROM PATIENTS ATTENDING DALHATU ARAF SPECIALIST HOSPITAL, LAFIA, NIGERIA
    (department of microbiology, Nasarawa State University, Keffi., 2015-04-04) Nkene, I.H.; Ngwai, Y.B.; Ungokore, H.; Atai, E.; Abdullahi, A.M.; Abah, E.J.; Abdullahi, U.; Zakou, M.A.; Ngadda, N.J.
    Staphylococcus aureus is a major commensal and pathogen of humans. Study on the antibiotic susceptibility of S. aureus from different clinical samples of patients attending Dalhatu Araf Specialist Hospital Lafia, Nigeria was carried out. A total of 100 urine samples, 30 ear swabs, 40 blood samples, 60 wound swabs, 30 High Vaginal Swabs (HVS) and 25 Endocer\ncal swab samples were collected from Februaiy to April, 2014. Staphylococcus aureus was isolated using standard method and antibiotic susceptibility test was carried out in accordance with the guidelines of the Clinical and Laboratory Standards Institute (CLS1). The frequency of S. aureus irrespective of the source of the sample decreased in order: High vaginal swab (36.7%) > Endocen>ical swab (28.0%) > urine (14.0%) > Blood (7.5%) > Ear swab (3.3%) > Wound swab (3.3%). The S. aureus isolates were highly susceptible to gentamicin (94.7%), ofloxacin (68.4%), ciprofloxacin (SI.6%) and streptomycin (52.6%) nitrofuratoin (50.0%) and less susceptible to pefloxacin (47.4%), augmentin (34.2%), ampicillin (23.7%), cotrimoxazole and ceftriaxone (5.3%) respectively. Thirty six (94.7%) of isolates showed multiple antibiotic resistance (MAR); MAR indices of 0.2 and above. The high susceptibility of the isolates to ciprofloxacin and gentamicin is evidence that these antibiotics may be useful for the treatment of S. aureus infections in this locality