Nwankwo, Oyinye Egonnaya2023-12-142023-12-142017-11-01https://keffi.nsuk.edu.ng/handle/20.500.14448/5953A study was carried out to determine the antibiotic susceptibility of bacteria and fungi associated with the second hand foot wears sold in Karu market and Wuse market, FCT Abuja, Nigeria. A total of 60 swab samples which comprised of 6 each were collected from the foot wears categorized into; industrial boot, foot ball boot, canvas, shoes and sandal. The result showed that mean total heterotrophic bacterial count ranged from 1.60 x 105 to 7.30 x 105(cfu/cm2), total coliform count 1.10 x 105 to 2.30 x 105(cfu/cm2), total faecal coliform count 0.00 to 1.10 x 105 (cfu/cm2) and total fungal count 1.30 x 105to 3.20 x 105(cfu/cm2). Predominant bacteria species identified were; Bacillus cereus, Staphylococcus aureus, Streptococcus pneumoniae and Pseudomonas aeroginosa. A total 5 fungi species; Penicillium citrinum, Aspergillus niger, Mucor spp, Trichophyton rubrum and Candida albicans were identified.. Percentage occurrence of bacteria isolated from second hand foot wears revealed that Bacillus cereus had and Pseudomonas aeruginosa had the highest frequency of 15(25.00%) each, followed by Staphylococcus aureus 7(11.67%) while Streptococcus pneumonia 4(6.67%) was the least occurred. On the other hand, fungi distribution showed that Aspergillus niger 15(25.00%) was the highest followed by Mucor spp 11(18.33%), Candida albicans 8(13.33%), Penicillium citrinum 5(8.33%) and the least was Trichophyton rubrum 3(5.00%). The antibiotics susceptibility profile of bacterial isolates showed that Pseudomonas aeruginosa was the least susceptible followed by the Bacillus cereus however, Staphylococcus aureus was the most susceptible. In descending order, Perfloxacin> Ciprofloxacin> Streptomycin > Gentamicin were observed to be active against the bacterial isolates. These results demonstrate that the second hand foot wears can be colonized by microorganisms that are potential vehicles for infections and thus pose a great risk to human health. The resistance of bacterial isolates to the various classes of antibiotics raises a serious public health concern.enThesis