Haruna, Isa MohammedMukhtar, Muhammad IdrisSadiq, Abubakar Hussaini2023-12-142023-12-142020-11-241. Pam VA, Landan S, Pam DD, Gullek JF, Okoro J, Ogbu KI. et al. The prevalence of malaria and typhoid co-infection in pregnant women attending antenatal in Wuse general hospital Abuja, Nigeria. Scientific Journal of Veterinary Advances. 2015;4(6):39-50. 2. World Health Organization. World malaria report 2018: Global malaria programme Geneva, Switzerland. 2018;340. 3. Ukibe SN, Ikeako LC, Mbanugo JI, Ukibe NR, Obi-Okaro AC. Rate of malariatyphoid co-Infection among pregnant women attending antenatal clinics in Anambra State South-east Nigeria. International Journal of Tropical Medicine and Public Health. 2013;2(1):1-11. 4. Pam VA, Landan S, Adejoh VA, Pam DD, Danjuma K. Co-infection of malaria and typhoid fever among pregnant women attending antenatal clinics at General Hospital Wuse, Federal Capital Territory (FCT), Abuja, Nigeria. Nigerian Journal of Parasitology. 2018;39(2):30-35. 5. World Health Organization. World malaria Report; 2013. Accessed on 15 October, 2020 Available:http://kff.org/global-healthpolicy/ fact-sheet/the-global-malariaepidemichttps://keffi.nsuk.edu.ng/handle/20.500.14448/5926Aims: This study was conducted to evaluate the prevalence, co-infection and socio-demographic determinants of malaria and typhoid fever among pregnant women attending antenatal care at a primary health care facility in Central Nigeria. Study Design: The study was a cross sectional study. Place and Duration of Study: Keffi, Nasarawa State, between January and October, 2020. Methodology: Blood sample (4 ml) was collected from each of the 429 consenting pregnant women attending antenatal care at Primary Healthcare Centre main market, Keffi, Nasarawa State. Malaria parasite was detected from the blood samples using one-step malaria rapid diagnostic test kit (SD Bioline, Inc, USA) and was confirmed by Gimesa stained thin and thick film microscopy while typhoid fever was diagnosed using Cromatest widal commercial antigen suspension (Linear Chemicals, Barcelona, Spain). Data collected were analysed using Smith’s Statistical Package (version 2.8, California, USA) and P value of ≤ 0.05 was considered statistically significant. Results: Of the 429 pregnant women screened, 123(28.7%) had malaria, 33(7.7%) had typhoid fever while 12(2.8%) had malaria-typhoid co-infection. Malaria-typhoid co-infection was found to be higher among pregnant women aged ≤30 years (3.5%), traders (3.9%), with primary education (3.2%) and who were from rural areas (6.3%). However, only location of the pregnant women was associated with the rate of malaria-typhoid co-infection (P< 0.05) whereas age, educational status and occupation were independent of the co-infection (P> 0.05). Conclusion: We confirmed the presence of malaria-typhoid co-infection among pregnant women in the study area. Considering it adverse effects on pregnancy and it outcome, there is need for more efforts towards it prevention, control and management.enMalaria; typhoid; infection; pregnant women; North; Nigeria.Article