Emmanuel, Atanyi YusufOduwole, H.K.Umar, Mallam Abdulkarim2023-12-142023-12-142023-01-19Umar, M.A. et al. (2023) Mathematical prototype for the control of malaria by interrupting the life cycle of the Anopheles mosquito through the use of biological enemies in the larva, pupa and adult stageshttps://keffi.nsuk.edu.ng/handle/20.500.14448/5776Mathematical prototype to fight malaria by interrupting the life cycle of the Anopheles mosquito through the use of biological enemies in the larval, pupal and adult stages has been derived to eradicate larvae, pupae and adult Anopheles mosquitoes using natural predators. The new model is a control flowchart of the predator-prey interaction model in the mosquito life cycle, considering an open population of mosquitoes and predators. These models provide a osolid understanding of malaria control in our environment, especially when models are based on vector population ecology; and a solid understanding of transmission-relevant parameters and variables Model equations were derived using parameters and variables from the model Stability analysis of free equilibrium states was analyzed simultaneously using equilibrium point, Maple software, elimination and substitution methods. The number of larvae that pupate is almost zero, and the number ofp upae that turn into adults is minimal, and the number of adults that'escape to the vector stage is negligible, which means that thd life cycle could be disrupted at larval, pupal and adult stages with the introduction of natural enemies, with the natural implication 'there will be no adult Anopheles mosquito for transmission of the malaria. The contribution of this research to knowledge is to produce the model or the mathematical formula and the biologically sound methods that will contribute to the eradication of the adult Anopheles mosquito, which will also lead to° the eradication of malaria in our society.enMathematical prototype; Biological enemies; Anopheles; Control; MalariaArticle