Bassey, A.Istifanus, Haruna NkeneBassey, B.E.Abimiku, Rejoice HelmaParom, S.K.Ngwai, Y.B.2023-12-142023-12-142020-05-131. Adenipekun, E.O., Jackson, C.R., Ramadan, H., Iwalokun, B.A., Oyedeji, K.S., Frey, J.G., Baretti, J.B., Hiott, L.M., Woodley, T.A. and Oluwadun, A. (2016). Prevalence and multi-drug resistance Escherichia coli from community-acquired infection in Lagos, Nigeria. Journal of Infection in Developing Countries, 10 (9):920-931. 2. Assafi, M.S., Ibrahim, N.M.R., Hussein, N.R., Taha, A.A. and Balatay, A.A. (2015). Urinary bacterial profile and antibiotic susceptibility pattern among patients with urinary tract infections in Duhok City, Kurdistan Region, Iraq. International Journal of Pure. Applied Science and Urology, 30:54-63. 3. Cheesebrough, M. (2006). Medical Laboratory Manual for Tropical Countries. Cambridge: Cambridge University Press, Pp. 49-97. 4. Clinical and Laboratory Standards Institute (2017). Performance Standards for Antimicrobial Susceptibility Testing; 27nd Informational Supplement M100-S22. Wayne, Pa, USA. 5. El bouamri, M.C., Arsalane, L., Zerouali, K., Katfy, K.,El kamouni, Y. and Zouhair, S. (2015). Molecular characterization of extended spectrum β- lactamase-producing Escherichia coli in a university hospital in Morocco, North Africa. African Journal of Urology, 21, 161–166. 6. Giwa, F.J., Ige, O.T., Haruna, D.M., Yaqub, Y., Lamido, T.Z. and Usman, S.Y. (2018). Extended-spectrum β-lactamase production and antimicrobial susceptibility pattern of uropathogens in a tertiary hospital in North-Western, Nigeria. Annals of Tropical Pathology, 9(1):11-16. 1930https://keffi.nsuk.edu.ng/handle/20.500.14448/5914Escherichia coli (E. coli) is among the most predominant organisms causing urinary tract infections (UTIs) in humans. Studies on antimicrobial resistance in E. coli from urine of patients in Nigerian National Petroleum Corporation Medical Services, Abuja, Nigeria was carried out. Exactly 362 urine samples of patients with suspected UTIs were collected and E. coli was isolated and identified using standard microbiological methods. The antimicrobial susceptibility testing of the isolates was carried out and interpreted in accordance with Clinical and Laboratory Standards Institute protocol. Of the 362 urine samples, the occurrence of E. coli was 45(12.4%); highest age-related occurrence at 21-30yrs of 18(20.5%); and higher in female (15.6%) than male (7.6%). The 45 isolates had highest resistance to ampicillin 43(95.6%) and lowest resistance to gentamicin 13(28.9%). All the 45 isolates were multiple antibiotic resistant (MAR) isolates with MAR indices of > 0.2, and the commonest indices being 0.6 and 0.7 with 10(22.2%) and 8(17.8%) occurrences respectively. The order of occurrence of categories of antibiotic resistance in the 45 isolates was: multi-drug resistance (66.7%) > extensive drug resistance (17.8%) > non-multidrug resistance (13.3%) > pan drug resistance (2.2%). A further study on molecular diversity of the antimicrobial resistant E. coli from urine in the study location is ongoing. 1926enEscherichia coli; microbial resistance; urine, patientsArticle