Olisenekwu, Lawrence Chuks2023-12-142023-12-142019-11-10BEING A DISSERTATION SUBMITTED IN PARTIAL FULFILLMENT OF THE REQUIREMENT FOR THE AWARD OF POST GRADUATE DIPLOMA IN BIOCHEMISTRYhttps://keffi.nsuk.edu.ng/handle/20.500.14448/5435Mining activities can cause untold health hazards on the lipid profile, liver and kidney functions in the inhabitants of Azara town. The level HDL-c was lower compared to the reference range and the level of LDL-c was higher than the reference range. This result suggests that the . inhabitants are predisposed to CVDs. Enzyme markers like ALP, AST, and ALT were elevated which connotes a possibly liver malfunction. Meanwhile, the GFR value was found to be in stage of CKD. Therefore, the use of antioxidants to reduce the increase of ROS to improve the health of aging men and to reduce the oxidative stress rate is recommended . Understanding the effect of crude mining methods could help the inhabitants to stay out of harm's way.enThesis