Maisalatee, A.U.Lumbi, W.L.Ewa, I.I.Mohammed, M.Kaika, Y.K.2023-12-142023-12-142020-07-301. El Naschie MS. A review of E-infinity theory and the mass spectrum of high energy particle physics. Chaos, Solitons and Fractals. 2004;19;209-236. 2. Marek-Crnjac L. Quantum Gravity in Cantorian Space-Time, Quantum Gravity, Dr. Rodrigo Sobreiro (Ed.). 2012;87-88. ISBN: 978-953-51-0089-8. 3. Ord G. Fractal space-time. J. Phys. A: Math. Gen. 1983;16;18-69. 4. Ord G. Entwined paths, difference equations and the Dirac equation. Physics Review A. 2003;67:0121XX3.https://keffi.nsuk.edu.ng/handle/20.500.14448/6005In this research work, the Riemannian Laplacian operator for a spherical system which varies with time, radial distance and time was obtained using the great metric tensors and a varying gravitational scalar potential. Furthermore the obtained Laplacian operator was used to obtain the generalized quantum mechanical wave equation for particles within this field. The Laplacian operator obtained in this work reduces to the well known Laplacian operator in the limit of c0 , and it contained post Euclid or pure Riemannian correction terms of all orders of c2 . Also the generalized quantum mechanical wave equation obtained, in the limit of c0 reduces to the well known Schrodinger mechanical wave equation, and in the limit of c2 contained additional correction terms not found in the well known Schrodinger wave equation. Hence the results in this work satisfy the Principle of Equivalence in Physics.enRiemannian; minkowski; laplacian; schrodinger; scalar potential.Article