Probiotics Potentials in Mitigating Coronavirus Disease (COVID-19) Pandemic

Date

2021-02-18

Journal Title

Journal ISSN

Volume Title

Publisher

Department of Microbiology, Nassarawa State University Keffi,

Abstract

Despite the adoption and use of different infection prevention and control measures, the coronavirus disease (COVID-19) pandemic keeps surging on with globally increasing morbidities and mortalities. The lack of a specific therapeutic intervention against COVID-19 warrants the use of non-conventional potent alternatives. In recent times, probiotics have shown to mitigate numerous health challenges, including animal and human infectious diseases through competitive exclusion or antagonism of pathogens, modulation of host-microbiota, secretion of antimicrobial compounds and stimulation of immune responses. The presentation of COVID-19 as severe respiratory distress leading to gastrointestinal tract involvement could be mitigated through probiotics administration which beneficially modulates the microbiota and immune responses with an attendant reduction in morbidities, hence curtailing the COVID-19 pandemic

Description

Keywords

COVID-19, pandemic, probiotics, microbiota, mitigate, prevention

Citation

1. World Health Organization (WHO). Weekly operational update on COVID-19 - 19 January, 2021. 2. Baud D, Dimopoulou AV, Gibson GR, Reid G, Giannoni E. Using probiotics to flatten the curve of coronavirus disease COVID-2019 pandemic. Front Public Health. 2020;8: 186. PubMed| Google Scholar 3. Cortegiani A, Ingoglia G, Ippolito M, Giarratano A, Einav S. A systematic review on the efficacy and safety of chloroquine for the treatment of COVID-19. J Crit Care. 2020;57: 279-283. PubMed| Google Scholar 4. Martinez MA. Compounds with therapeutic potential against novel respiratory 2019 coronavirus. Antimicrob Agents Chemother. 2020;64(5): e00399-20. PubMed| Google Scholar

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