Behaviours of liver and kidney function markers in diabetic rats treated with Calotropis procera leaf aqueous extract

long-term high biood giucose 0010565 diabetes me hits; this metabolic disorder is accompanied لالأ both short - and long terms complications. In the present study, behaviours of liver and kidney function markers in diabetic rats treated with different doses of Caiotropis procera ieaf aqueous extract were studied. At p>0.05, the biood giucose, hepatic GOT, GPT, albumin, total bilirubin, GOTZGPT ratio, serum urea and creatinine were significant^ elevated in diabetic groups (6 ر, D, E and 1٢) while hepatic gogen was significant^ reduced with induction of alloxan. Treatment with the extract at different doses of administration (25, 50 100mg/kg .ا.) particular^ higher doses restored the markers back to their normal levels when compared to mean values of non-diabetic group (A). Mean values of markers in group administered 100mg/kg b.w. dose of non-diabetic and metformin groups (4 and 3) were in the same In the present std, it can be deduced that aqueous of 04/0٤/02٨0٥/0/ 25ر leaf at 100 mgkg .ا dose showed significant potency in amelioration of alloxan disturbances on hepatic and renal function markers.