Prevalence and determinants of hepatitis B virus infection among human immunodeficiency virus patients at a tertiary health care facility in Central Nigeria
| dc.contributor.author | Alaku, Sarah | |
| dc.contributor.author | Haruna, Isa Mohammed | |
| dc.contributor.author | Pennap, Grace Rinmecit | |
| dc.date.accessioned | 2023-12-14T07:43:12Z | |
| dc.date.available | 2023-12-14T07:43:12Z | |
| dc.date.issued | 2020-04-30 | |
| dc.description.abstract | Hepatitis B virus (HBV) co-infection with human immunodeficiency virus is a major public health problem especially in developing countries. In this study, the prevalence of HBV infection was evaluated among 400 consenting HIV patients accessing healthcare in Federal Medical Center, Keffi, Nigeria using HBsAg detection as the surrogate. Blood samples were collected and screened for HBsAg using ACON screening kit (ACON Laboratories Inc, USA). The Chi-square statistical test was performed to identify possible determining factors associated with the viral infection. Overall, 30 (7.5%) of the participants were reactive to HBsAg. The possible determining factors for acquiring the virus recorded in this study were marital status and alcoholism (p<0.05). Gender, age, educational status, occupation, history of blood transfusion, locality, cigarette smoking, self-manicure and pedicure, tribal marks, tattoos and history of HBV vaccination were not significantly associated with acquiring the viral infection (p>0.05). This finding calls for a concern because coinfection of HBV with HIV accelerates disease progression and also has an effect on the management of patients infected with HIV. | en_US |
| dc.identifier.citation | [1] World Health Organization (WHO). (2016). What is Hepatitis? [2] Akmal M, Zulkifle M and Arisari AH. (2015). Assessment of awareness of hepatitis B virus infection in the patients attending Nium, Bangalore, India. International Research Journal of Pharmacy, 6(3), 210-212. [3] Sarkar J, Saha D, Bandyopadhyay B, Saha B, Kedia D, GuhaMazumder GDN, RunuChakravarty R and Kamal SG. (2016). Baseline characteristics of HIV & hepatitis B virus (HIV/HBV) co-infected patients from Kolkata, India. Indian Journal of Medical Research, 143, 636-642. [4] Pennap GR, Yakubu A, Oyige O and Forbi J. (2010). Prevalence of hepatitis B and C virus infection among people of a local community in Keffi, Nigeria. African Journal of Microbiology Research, 4(4), 274-278. [5] Negussie A and Beyene E. (2016). Seroprevalence of hepatitis B Surface antigen among pregnant women attending antenatal clinic in Jigjiga, East Ethiopia: A Cross-Sectional Study. International Journal of Research and Review, 3(2), 1-7. | en_US |
| dc.identifier.uri | https://keffi.nsuk.edu.ng/handle/20.500.14448/5933 | |
| dc.language.iso | en | en_US |
| dc.publisher | Department of Microbiology, Nasarawa State University, Keffi | en_US |
| dc.subject | Hepatitis B surface antigen; HIV; Co-infection; Nigeria | en_US |
| dc.title | Prevalence and determinants of hepatitis B virus infection among human immunodeficiency virus patients at a tertiary health care facility in Central Nigeria | en_US |
| dc.type | Article | en_US |