Browsing by Author "Solomon, M."

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    IMMUNE SYSTEM RESPONSE TO CHANGES.IN DIFFERENT ’ ANTIOXIDANT DIETARY INTERVENTION ON STAFF OF NASARAWA STATE UNIVERSITY, KEFFI
    (Department of Zoology, Nasarawa State, University Keffi, 2017-03-03) Nweze, C.C.; Solomon, M.; Andrew, Yako B.; Enemali, M.O.; Ijeomah,A.U.
    Effect of antioxidant functional foods and nutraceuticals on malortdkldehyde (MBA) level, cytotoxic clusters . of differentiation antigen 4 (CD4) and Immunoglobulin M (IgM) in male and female individuals were studied-. for six months. The volunteers included a total of 150 healthy adults of 96 men and‘54 women aged between 30 and 74 years. They were made ursign an informed consent form, questioner and unethical approval was gotten;* *' At the baseline, eligible candidates were randomized to either 1 capsule per day of antioxidant! nutraceutical (Forever living product) (containing vitamin E 10 mg, vitamin C 60mg and (i- carotene 2000 nieg of vitamin • A, or cheap affordable indigenous antioxidant functional foods of equivalent vitamin composition of orang&s,’. carrots, and soybean or bottled w.ater, and the first dose was dispensed and followed up for six months. There was a positive decrease in MDA. and IgM values and a positive increase in CD4 counts after antioxidant dietary intervention. However, a lower concentration of MDA, and higher level of IgM and CD4 in men than in female at some age ranges was observed. The study showed that the indigenous antioxidant functional foods could be used as an alternative to the expensive imported antioxidant nutraceuticais in boosting.immunity and therefore suggest such for immune- compromised individuals especially in developing countries like Nigeria. • 0 ;
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    PLASMA ANTIOXIDANT MICRO NUTRIENTS LEVEL OF APPARENTLY HEALTHY ADULTS AFTER A DIETARY INTERVENTION BASED ON AGE AND GENDER IN NASARAWA STATE UNIVERSITY, KEFFI, NIGERIA
    (Department Of Zoology, Faculty Of Natural And Applied Sciences, Nasarawa State University, Keffi, 2006-04-22) Nweze, C.C.; Solomon, M.; Andrew, Yako B.; Ijeoma, A.U.
    Immunologic functions, particularly cell-mediated immunity, declines with age, contributing to the increased incidence of infectious diseases in the elderly. The study looked at vitamin C, vitamin E, and a-carotene levels in plasma of 150 healthy adults of 96 men and 54 women aged between 30 and 74 years. The subjects were randomly grouped into three at baseline for further dietary studies. Either 1 capsule per day of antioxidant nutraceuticai (Forever living product) (containing vitamin E 10 mg, vitamin C 60mg and a- carotene 2000 meg of vitamin A) or cheap and affordable indigenous antioxidant functional foods of equivalent vitamin composition oforanges, carrots, and soybean bottled water. The first dose was dispensed and followed up for six months. The result showed that the vit C, E and a- concentration of antioxidant treated groups were or carotene positively influenced titan the placebo group Gm 1 CAT m Grp 3 (AT-F). was affected more positively than the ant oxidant' Grp 2 (AT-N) Vitamin C, E, and a-carotene concentrations of the elderly are beyond reference/norma] range of blood p|asma.
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    Serum lipoproteins response to twelve months changes in antioxidants: Influence of nutraceuticals and functional foods intervention on age and gender
    (Department of Biochemistry, Nasarawa State University Keffi, 2018-12-08) Nweze, C.C.; Solomon, M.; Haruna, Sunday Gambo
    The bioactive compounds in encapsulated-nutraceuticals have contributed to reducing oxidative stress. The cost of these encapsulated extracts makes them unaffordable to the low income groups in developing countries such as Nigeria. Thus, the search for alternative affordable antioxidant functional foods is best alternative. This study investigated effect of two antioxidants on blood lipids and lipoproteins. The study was undertaken by healthy volunteers of 96 males and 54 females within the ages of 30-74 years old. Volunteers were randomly divided into three groups and blood samples collected at intervals of baseline and six months. Volunteers were randomized to either 1 capsule per day of antioxidant nutraceutical, antioxidant functional foods or placebo. Blood samples were analysed for Cholestrol, Tryglyceride, LDLc, HDLc, and Uric acid at baseline and twelve monrhs. All were significantly reduced (p<0.05), exception of HDLc that significantly increased (p<0.05). The study indicates that functional foods antioxidants improved the serum lipids and lipoproteins indices.