Browsing by Author "Pennap, G.R."

Now showing 1 - 3 of 3
  • Thumbnail Image
    ItemOpen Access
    Antibiotic resistance in Escherichia coli from urine of patients with suspected urinary tract infections accessing Dalhatu Araf Specialist Hospital, Lafia, Nigeria
    (Department of Microbiology, Nassarawa State University Keffi,, 2019-08-20) Nkene, I.H.; Ngwai, Y.B.; Bassey, E.B.; Pennap, G.R.; Makut, D.M.; Abimiku, R.H.; Ibrahim, T.; Tsaku, P.A.
    The wide use of antibiotics to treat urinary tract infection (UTIs) caused by bacteria is compromised by the development of resistance mechanisms in bacteria. This study evaluated the antibiotic resistance in Escherichia coli from urine of patients with suspected UTI in Dalhatu Araf Specialist Hospital, Lafia, Nigeria. Four hundred urine samples of suspected UTI patients were collected and E. coli was isolated and identified using standard microbiological methods. Antimicrobial Susceptibility Testing for the isolates was carried out and interpreted as described by the Clinical and Laboratory Standards Institute (CLSI). The occurrence of the bacterium was 14.5 % (58/400). The occurrence was higher in female (15.8 %) than the male (12.5 %); and highest at > 50 years (31.8 %). The isolates were more resistant to ampicillin (79.3 %), streptomycin (62.0 %) and cefoxitin (58.6 %) but less resistant to gentamicin (15.8 %), imipenem (18.9 %) and amoxicillin/clavulanic acid (27.6 %). The occurrence of multi-drug resistance (MDR) isolates was 87.9%. The antibiotics namely gentamicin, imipenem and amoxicillin/clavulanic acid were very effective against the isolates and most of the isolates were MDR. There is thus a need for the hospital to limit its antibiotic use in the light of these observations.
  • Thumbnail Image
    ItemOpen Access
    Hepatitis B Virus Carriage among Students of a Nigerian Tertiary Institution: A Cohort of Eligible Blopd Donors
    (Department of Zoology, Nasarawa State University, Keffi., 2011-09-23) Pennap, G.R.; Nwachukwu, O.; Ishaleku, D.; Ombugadu, Ruth Jamila
    Hepatitis B virus infection may go unnoticed because >50% of the cases are subclinical. Infected people therefore either unconsciously contribute to the transmission*of the virus or do not seek medical attention with a resultant liver cirrhosis or. hepatocellular carcinoma. This gtudy was mooted to provide a prevalence baseline data in a cohort that is eligible for blood donations with a view to instituting proactive prevention programmes. About 200 students that indicated willingness to participate in this study'were recruited. About 5 mL of venous blood was taken from each student and the resultant serum screened for Hepatitis B surface antigen (HBsAg) using smart Check HBsAg ELISA (Giobalmed, South Africa (PTY) Cape Town). Positive samples were confirmed with Clinotech HBsAg test kit (Clinotech diagnostic and Pharmaceuticals, Canada). Screening was performed according to the manufacturers instructions. Of the 200 samples screened, 23 (11.5%) tested positive. There was no statistically significant association between the viral infection and gender, age, having multiple sex partners, possession of tribal marks and dmg injections (p>0.05). This prevalence of 11.5% is a cause for alarm especially in a cohort that is eligible for blood donation. It is therefore necessary to intensify health promotion efforts in the tertiary institutions.
  • Thumbnail Image
    ItemOpen Access
    INTESTINAL PROTOZOANS AND HELMINTHES IN PATIENTS ATTENDING A K WANG A GENERAL HOSPITAL, NASARAWA STATE, NIGERIA
    (Department of Zoology, Nasarawa State University, Keffi., 2012-09-30) Ombugadu, Ruth Jamila; Pennap, G.R.; Hussaini, F.A.