Browsing by Author "Arije, Damilare Olaniyi"

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    Applications of Myostatin in Poultry and Aquaculture - A Review
    (Department of Animal Science, Nasarawa State University, Keffi., 2022-05-25) Shoyombo, Ayoola John; Yakubu, Abdulmojeed; Alabi, Olayinka Olubunmi; popoola, Mustaph Ayodele; Okon, Ekemini Moses; Arije, Damilare Olaniyi
    Polymorphism is an important component of animal genetic improvement. As a result, myostatin gene is largely involved in muscle formation and growth and is a great candidate gene for increased growth of muscle in animals. Myostatin negates the growth of muscle cells and is found across species. Literature shows various applications and importance of myostatin in poultry and aquaculture production. In poultry, variations in the myostatin gene have been linked to growth characteristics. In aquaculture, myostatin influences the enhancement of the muscle tissues of fish. Besides, myostatin plays a role in increasing the lipid content of muscle, lowering circulating glucose levels, and hepatosomatic index in fish. Studies on zebrafish as a model species have confirmed myostatin involvement in the muscle development of fish. Its expression is not limited to skeletal muscle but also occurs in the liver, brain, and other organs. In the myostatin-b-deficient zebrafish, the size of visceral adipose tissues shrank, and more lipids have been observed to accumulate in skeletal muscle than in wild-type fish. The inhibition or complete depletion of functional myostatin is known to cause the “double-muscled” in several cattle breeds and similar traits in other species. However, the “doublemuscled” animals have captured the attention of breeders and researchers due to the enhanced muscular tissues; associated with productivity issues. For instance, the effect of myostatin inhibition has been associated with egg production. When compared to wild-type, myostatin homozygous mutant birds had a significantly delayed commencement of egg production in layers. It is therefore imperative to increase the knowledge of myostatin molecular genetics and bioactivity in various tissues in the poultry and aquaculture sector. This will enable improved productivity and enhanced contribution of animal-sourced proteins from both sectors of animal production.