Browsing by Author "Ajayi, J.A,"
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Item Open Access DETERIORATION OF CD4 T-CELLS IN HIV/AIDS INDIVIDUALS INFECTED WITH PATHOGENIC MICROSPORIDIUM IN BENUE STATE, NIGERIA.(Department Of Zoology, Faculty Of Natural And Applied Sciences, Nasarawa State University, Keffi., 2013-05-13) Andrew, Yako B.; Ajayi, J.A,; Makpo, James Kpuk; Auta, K.I.Preliminary survey in Benue State shows that 96 HIV/AIDS individuals were infected with pathogenic microsporidium. 966, 42 (4.3%) males CD., T-cells count were <335 cell/pl, and in the female category 1042, 54 (5.2%) CDj T-celis were <320 cell/pl at the first C04 pathogenic microsporidium in M1V/A1DS individuals was observed as a leading-cause of diarrhea, and a fall in the CD4 T-cells count after 90 days • of re-evaluation. Among the age group of 30-39 years, the CD4 cells count gradually deteriorate to <200 cell/pl indicating high risk to acquired immune deficiency syndrome (AIDS) and opportunistic• infections. However, there was a significant relationship among sexes given that, Z=1.039<±1.96 in other words, microsporidium was solely depended on age which shows no significant relationship among the age groups count. The strain of ; (x2=7.815>0.05).Item Open Access Immune prolile of HIV+with microsporidium and Hepatitis-B in Benue State, Nigeria(Department Of Zoology, Faculty Of Natural And Applied Sciences, Nasarawa State University, Keffi., 2011-04-11) Andrew, Yako B.; Ajayi, J.A,; Makpo, James Kpuk; Auta, K.I,; Nweze, C.C,; Banyigyi, H.ASurvey was focused exclusively on human excreta and sera for microsporidium and hepatitis- B.The immune profile was determined ofHIV-Y individuals in Benue State. Intestinal epithelium was the most prevalent site of human microsporidium infection, 54 (4:2%) were infected in both ' sexes. Enterocylozoon bieneusi was most prevalent in Makiirdi with no significant relevance in the spread of microsporidium species among a cohort population study (r=0.79 >0.60, df-9). Urinary tract microsporidiosis appears in 31(2.4%)) patients• with Encephalitozoon cuniculi although, many-persons during these findings do not have symptoms referable to the urogenital route and 9(1:3%) were HBsAg-V with no significant difference since r-0.76>0.75, df-6. Stools were loose to watery and co- infected with laboratory evidence for intestinal microsporidium in 1(0.5%) with T-cells < 80 cell7pi. However, sexual transmission of microsporidiosis cannot be excluded. Therefore, the clinical spectrum of the disease should be tied to thorough laboratory investigation and strict hygienic condition should be maintained.